World’s First,
Global Pioneer in
Tiger Milk Mushroom Cultivation
From Malaysia’s rainforests, LiGNO Biotech pioneered the world’s first cultivation of the Tiger Milk Mushroom, transforming a centuries-old tradition into a clinically validated wellness solution.






ADVANCING SCIENCE, CULTIVATING HEALTH
Our R&D Mission
Research and development is at the core of everything we do. Through patented cultivation technology and clinical research, LiGNO Biotech sets the global benchmark for safety, efficacy, and consistency in functional mushroom solutions.
Our R&D Journey
Not all mushroom ingredients are created equal. Every LiGNO ingredient undergoes rigorous testing and clinical validation to confirm real-world health benefits.
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Peer-reviewed publications on medicinal mushrooms
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Laboratory and clinical studies on safety, bioactivity, and dosage
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Conference presentations on functional mushrooms & biotechnology
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Completed clinical trials on immunity, respiratory health, and metabolism
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Global partnerships with universities, hospitals, and research institutions
Nutraceuticals & Supplements
278+
Types of waste we collect
We've got the permits to handle all kinds of waste.
278+
Types of waste we collect

We've got the permits to handle all kinds of waste.
Standardized bioactive for immunity, energy, and wellness.
278+
Types of waste we collect
We've got the permits to handle all kinds of waste.
OUR R&D FOCUS
We partner with health and wellness brands to bring your mushroom-based product ideas to life. Our expertise lies in developing and supplying the core ingredients and formulations for various industries, including:
Science
Evidence-based innovation driven by rigorous research.
Heritage Agriculture
Sustainable cultivation rooted in biodiversity.
Societal Health
Functional solutions that improve quality of life worldwide.
Our R&D Focus
We partner with health and wellness brands to bring your mushroom-based product ideas to life. Our expertise lies in developing and supplying the core ingredients and formulations for various industries, including:
Science
Evidence-based innovation driven by rigorous research.
Heritage Agriculture
Sustainable cultivation rooted in biodiversity.
Societal Health
Functional solutions that improve quality of life worldwide.
Nutraceuticals & Supplements
278+
Types of waste we collect
We've got the permits to handle all kinds of waste.
278+
Types of waste we collect

We've got the permits to handle all kinds of waste.
Standardized bioactive for immunity, energy, and wellness.
278+
Types of waste we collect
We've got the permits to handle all kinds of waste.
Scientific Leadership
Led by Dr. Tan Chon Seng
Recognized as the Patriarch of the Tiger Milk Mushroom, Dr. Tan Chon Seng brings decades of expertise in clinical and translational research. He has authored numerous patents and scientific publications, working in collaboration with leading hospitals and universities across Malaysia and around the world.
Dr. Tan Chon Seng,
BSc, MSc, PhD, FASc
Biochemistry, Cell & Molecular Biology
- Specialist in functional mushroom cultivation and agricultural sciences
- Over 30 years as Principal Research Officer at MARDI Biotechnology Research Centre
- Extensive expertise in tropical agriculture and biotechnology innovation
Scientific Advisory Board
Our R&D is guided by a panel of experts in biochemistry, pharmacology, and molecular biology. Our Scientific Advisory Board ensures that every R&D initiative blends rigorous science, traditional wisdom, and real-world health impact.
Professor ChM Dr. Fung Shin Yee, BSc (Hons), MMedSc, PhD
Biochemistry & Medicinal Mushroom Research
- Professor of Biochemistry, Universiti Malaya
- Principal Investigator and Head of Medicinal Mushroom Research Group (MMRG)
- Pioneer in research on safety, efficacy, and bioactivity of medicinal mushrooms, especially Tiger Milk Mushroom (Lignosus sp.)
- Multiple patent holder; recipient of prestigious awards
- Founder & CTO of Essenti Nutrien Sdn. Bhd., developer of ACE Technology
Professor Dr. Ting Kang Nee, BPharm (Hons), PhD, PGCHE, Fellow (HEA)
Pharmacology
- Professor of Physiology & Pharmacology, University of Nottingham Malaysia
- Registered Pharmacist (Malaysia Pharmacy Board, General Pharmaceutical Council UK)
- Research expertise in pharmacological effects of plant- and mushroom-derived compounds on smooth muscles and calcium channel studies
- Active research collaborations with Monash University (Australia), University of Leeds (UK), and University of Hull (UK)
Dr. Kuan Chee Sian, BBiomed, PhD
Biomedicine, Molecular & Cell Biology
- Specialist in medical diagnostics and regenerative medicine
- Founder & Managing Director, NeoGenix Laboratoire Sdn. Bhd.
- Director, HS-Bio (subsidiary of Hong Seng Consolidated Berhad)
- CEO, Strait Genomics Sdn. Bhd.
Global Research Partners
Since 2010, LiGNO Biotech has advanced functional mushroom science through strategic partnerships with top-tier universities and research institutions. These collaborations drive clinical validation, uncover new applications, and foster global innovation, solidifying our status as the world’s leading Tiger Milk Mushroom expert and first cultivator.
Partner with the Global Leader in Functional Mushrooms
Bring science-backed, clinically validated mushroom ingredients to your products with LiGNO Biotech.
Partner with the Global Leader in Functional Mushrooms
Bring science-backed, clinically validated mushroom ingredients to your products with LiGNO Biotech.




















